PIK3CA (E545K Mutant)/PIK3R1 Proteins

PIK3CA (E545K Mutant)/PIK3R1 Human recombinant proteins are validated for use in the following applications: Kinase Assay. These proteins are expressed in Insect cells. Available Product Grades: RUO. Browse all 2 proteins. Not finding the exact protein, grade or size needed?... PIK3CA (E545K Mutant)/PIK3R1 Human recombinant proteins are validated for use in the following applications: Kinase Assay. These proteins are expressed in Insect cells. Available Product Grades: RUO. Browse all 2 proteins. Not finding the exact protein, grade or size needed?... PIK3CA (E545K Mutant)/PIK3R1 Human recombinant proteins are validated for use in the following applications: Kinase Assay. These proteins are expressed in Insect cells. Available Product Grades: RUO. Browse all 2 proteins. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.... PIK3CA (E545K Mutant)/PIK3R1 Human recombinant proteins are validated for use in the following applications: Kinase Assay. These proteins are expressed in Insect cells. Available Product Grades: RUO. Browse all 2 proteins. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.

Protein Information

PIK3CA E542K/PIK3R1 (p110 alpha E542K/p85 alpha) lipid kinase is comprised of a 110 kDa catalytic subunit and an 85 kDa regulatory subunit. A number of isoforms of the 110 kDa catalytic subunit and the 85 kDa regulatory subunit exist in cells. PIK3CA is frequently mutated or amplified in a variety of cancers including ovarian and colon and this kinase is one of the PI3K mutants. PIK3CA gene copy number is increased in over 30% of ovarian cancers and this leads to increased PI3-kinase activity. Furthermore, the activity of PIK3CA is essential for vascular development and inactivation of PIK3CA leads to severe defects in angiogenic sprouting and vascular remodeling.

Synonyms

PIK3CA; PIK3R1

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Invitrogen

Human PIK3CA E542K/PIK3R1 (p110 alpha E542K/p85 alpha), His Tag Recombinant Protein

Invitrogen

Human PIK3CA E542K/PIK3R1 (p110 alpha E542K/p85 alpha), His Tag Recombinant Protein

Species

Human

Expression System

Insect cells

Product Grade

Research Use Only

Application

Price

Cat # A33518

Invitrogen

Human PIK3CA E545K/PIK3R1 (p110 alpha E545K/p85 alpha), His Tag Recombinant Protein

Invitrogen

Human PIK3CA E545K/PIK3R1 (p110 alpha E545K/p85 alpha), His Tag Recombinant Protein

Species

Human

Expression System

Insect cells

Product Grade

Research Use Only

Application

Price

Cat # A31083

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PIK3CA (E545K Mutant)/PIK3R1 Proteins

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